EIT-based ventilation phenotypes of left-to-right asymmetry and ventral-to-dorsal center in PEEP titration in ARDS.

ABSTRACT:

Background

Ventilation distribution assessed by electrical impedance tomography (EIT) has great interests in acute respiratory distress syndrome (ARDS). The aim of the study was to explore ARDS phenotypes based on left-right and ventral-dorsal ventilation distribution and to investigate their clinical characteristics and outcomes.

Method

This retrospective study included ARDS patients from two ICUs who underwent mechanical ventilation and EIT monitoring. Asymmetry index (AI) was defined as the right-to-left ventilation difference in percentage. Based on the AI at low PEEP (0-3 cmH₂O), patients were classified as asymmetric (|AI| > 20%) or symmetric (|AI| ≤ 20%) phenotype. Asymmetric phenotype was divided into right (R, AI > 20%) and left (L, AI < -20%) subphenotypes. Based o

SUBMITTER: Sun X 

PROVIDER: S-EPMC12905866 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature