Dataset Information
Integrating bioinformatic analyses and experimental validation of disulfidptosis-related genes and TMX4 in melanoma progression.
Ontology highlight
ABSTRACT:
SUBMITTER: Yi Y
PROVIDER: S-EPMC12905907 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature
Publications
Integrating bioinformatic analyses and experimental validation of disulfidptosis-related genes and TMX4 in melanoma progression.
Cancer cell international 20260120 1
BACKGROUND: Melanoma is a highly metastatic and lethal malignancy originating from melanocytes. Disulfidptosis is a recently discovered type of programmed cell death with promising potential in cancer therapy. This study aims to establish a prognostic risk model based on disulfidptosis-related gene signatures and investigate their roles in melanoma progression. MATERIALS AND METHODS: Transcriptomic data from the TCGA-SKCM and GEO databases were analyzed to identify disulfidptosis-related gene ex ...[more]