Foods Fortified with Soybean or Palm Oil Show No Effect on Inflammation or Oxidized Low-Density Lipoprotein in Adults with Overweight or Obesity: a Secondary Analysis of a Randomized Placebo-Controlled Crossover Trial.

ABSTRACT:

Background

Popular and social media outlets have recent posts claiming that vegetable and seed oils high in linoleic acid (LA) cause inflammation and oxidative stress. However, substantial evidence in the scientific literature shows LA biomarkers are associated with lower risks for type 2 diabetes, cardiovascular disease, and systemic inflammation.

Objectives

The primary aim of this study is to evaluate the impact of dietary fortification with soybean oil (high in LA) compared with palm oil on markers of systemic inflammation and oxidized low-density lipoprotein (oxLDL) in healthy overweight adult participants.

Methods

This double-masked crossover clinical trial consisted of 2 diet periods where adults with overweight or obesity were randomly assigned to receive 3 stu

SUBMITTER: Yang CT 

PROVIDER: S-EPMC12906016 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature