Impact of perioperative dexamethasone on postoperative complications in diabetic patients undergoing spine surgery.

ABSTRACT:

Background

Dexamethasone is commonly used perioperatively for analgesic and antiemetic benefit, however, the risk of postoperative hyperglycemia is concerning, particularly among diabetic patients undergoing spine surgery, where extensive tissue exposure and hardware implantation may increase risk of wound complications. The influence of baseline glycemic control and surgical approach on dexamethasone-associated risk remains poorly characterized.

Methods

A retrospective cohort study using the TriNetX United States Collaborative Network, a nationally representative database comprised of over 117 million unique patients, was conducted. Adults with diabetes mellitus who underwent spine surgery between 2014 and 2024 were identified and categorized into anterior cervical, posteri

SUBMITTER: Kim MS 

PROVIDER: S-EPMC12906027 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature