Toxicity of ivermectin on multiple insecticide-resistant populations of Anopheles gambiae sensu lato, Aedes aegypti, and Culex mosquitoes.

ABSTRACT:

Background

Ivermectin is an emerging vector control; however, its toxicity against insecticide-resistant mosquito populations with multiple resistance mechanisms remains unclear. This study investigated the toxic effects of ivermectin on three multiple insecticide-resistant mosquito populations from Ghana.

Methods

Susceptibility to different insecticides, target-site mutations associated with insecticide resistance, and metabolic resistance mechanisms were determined among field mosquito populations of Anopheles gambiae sensu lato, Aedes aegypti, Culex species, and susceptible Anopheles gambiae sensu stricto Kisumu (laboratory strain). Dose-response bioassays were performed by feeding the mosquito populations with different concentrations of ivermectin dissolved in a 10% sug

SUBMITTER: Obuobi D 

PROVIDER: S-EPMC12906033 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature