Thrombotic thrombocytopenic purpura: a Trojan horse of acute leukemia?: a case report.

ABSTRACT:

Background

Thrombotic thrombocytopenic purpura is a rare and life-threatening hematologic disorder. We present the case of a 66-year-old man who developed acquired thrombotic thrombocytopenic purpura as the first manifestation of acute myeloblastic leukemia. This case emphasizes the importance of considering underlying malignancy in atypical thrombotic thrombocytopenic purpura presentations.

Case presentation

We report the case of a 66-year-old Lebanese male patient, a heavy smoker, who presented with drowsiness and confusion; 1 month before his presentation, he presented with pruritic ecchymosis skin lesions, which were initially misdiagnosed as superinfected fungal lesions. Laboratory tests at the emergency department revealed bicytopenia (hemoglobin at 5.2 g/dL, platelets

SUBMITTER: Nassani BM 

PROVIDER: S-EPMC12906077 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature