Chinese thyroid imaging reporting and data system with redefined marked hypoechogenicity for thyroid malignancy risk stratification demonstrates improved diagnostic accuracy.

ABSTRACT:

Purpose

Using ultrasound to distinguish between benign and malignant thyroid nodules can be challenging. The purpose of this study was to evaluate the diagnostic performance of a modified Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) that incorporates a redefined criterion for marked hypoechogenicity in stratifying the malignancy risk of thyroid nodules.

Methods

In this retrospective study, we analyzed patients with thyroid nodules who underwent ultrasound examination and subsequent biopsy or treatment at a tertiary hospital between January 2022 and December 2023. Interobserver agreement in identifying marked hypoechogenicity between two reviewers was assessed using kappa statistics. Using histopathology as the reference standard, the diagnostic performance of

SUBMITTER: Bai Y 

PROVIDER: S-EPMC12906256 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature