Clinical Outcomes of Patients Who Underwent Palliative Surgery for Spinal Metastases With and Without a History of Radiation: A Multicenter Registry Study.

ABSTRACT: Study DesignA multicenter retrospective cohort study using prospectively collected data.ObjectivesRadiotherapy (RT) is the standard treatment for spinal metastases; however, the optimal timing of RT in patients requiring surgery remains unclear. This study compared the clinical outcomes of palliative surgery according to RT timing.MethodsAmong 413 patients screened across 35 centers, 146 patients with spinal metastases limited to the spine who underwent palliative surgery were included. Patients were classified into three groups based on RT timing: preoperative RT, postoperative RT, and no RT. Short-term outcomes were compared among the three groups.ResultsOf the 146 patients (preoperative RT: n = 42; postoperative RT: n = 59; no RT: n = 45), baseline characteristics and postoperative func

SUBMITTER: Kawamura I 

PROVIDER: S-EPMC12906389 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature