Access-Related Hand Dysfunction After Hemodialysis Access Placement.

ABSTRACT:

Introduction

Patients with chronic kidney disease (CKD) or end-stage kidney disease (ESKD) frequently experience access-related hand dysfunction (ARHD) following hemodialysis access placement, negatively impacting clinical outcomes and quality of life. Despite its prevalence, the mechanisms underlying ARHD remain poorly understood, and its impact on subsequent access maturation failure has not been well-characterized.

Methods

We conducted a longitudinal study of 39 patients with CKD or ESKD undergoing hemodialysis access surgery. Functional assessments, including grip strength, finger pressure, patient-reported hand or arm disability, dexterity, and sensory testing were performed preoperatively and 6 weeks postoperatively. Brachioradialis muscle biopsies were analyzed for mo

SUBMITTER: Kim K 

PROVIDER: S-EPMC12906999 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature