Short-term analysis of botulinum toxin A for functional popliteal artery entrapment syndrome.

ABSTRACT:

Objective

Functional popliteal artery entrapment syndrome (fPAES) is characterized by exertional leg pain caused by hypertrophic musculature in young adults. If history, examination and imaging suggest fPAES, treatment is surgical including removal of plantaris and part of medial gastrocnemius muscle. Intramuscular botulinum toxin type A (BTX) injections are a less invasive alternative, but the therapeutic evidence is low. The aim of this prospective study was to determine the short-term clinical effects of BTX.

Methods

In this prospective single-center cohort study, young patients with a history suggestive of fPAES (calf pain within 5-10 minutes after starting exercise, disappearance 5-10 minutes after exercise cessation) and suggestive imaging (occluding or stenotic poplit

SUBMITTER: Goossens SH 

PROVIDER: S-EPMC12907067 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature