Association of CT-derived body composition with coronary plaque components and vascular inflammation.

ABSTRACT:

Objective

To investigate the relationship of body composition with coronary plaque components and vascular inflammation.

Materials and methods

This retrospective study included 412 individuals who underwent computed tomography angiography scan between August 2024 and July 2025. Body composition including both muscle and adipose components was analyzed. Plaque characteristics and pericoronary fat attenuation index (FAI) were quantified. The associations between body composition, plaque burden, and FAI were examined using correlation and multivariable linear regression analyses. Furthermore, we explored the mediating roles of specific body composition metrics in the relationship between body mass index (BMI) and plaque burden, as well as the potential mediation by FAI in the a

SUBMITTER: Gao L 

PROVIDER: S-EPMC12907226 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature