Real-time guidance of lauromacrogol ablation for pancreatic cystic lesions using confocal laser endomicroscopy.

ABSTRACT:

Background

Needle-based confocal laser endomicroscopy (nCLE) can accurately identify the pathological types of pancreatic cystic lesions (PCLs), but there are no reports of real-time intraoperative guidance for lauromacrogol ablation (LA) therapy.

Objectives

This study aimed to assess the diagnostic accuracy and safety of nCLE in identifying the candidates for LA in the same session as endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA).

Design

Prospective study.

Methods

We performed a prospective study of patients with PCL who underwent EUS-FNA and nCLE at the First Medical Center of Chinese PLA General Hospital between February 2024 and June 2025. The diagnostic performance of nCLE in intraoperatively differentiating concomitant ablation-eligible le

SUBMITTER: Hao X 

PROVIDER: S-EPMC12907481 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature