Causal Association of Dietary Habits With Thyroid Diseases: Univariate and Multivariate Mendelian Randomization Studies.

ABSTRACT: Dietary habits play a crucial role in everyday health, influencing both the onset and progression of diseases. Previous studies have shown some effects of dietary habits on certain thyroid diseases. However, comprehensive research on the causal relationship between dietary habits and thyroid diseases is lacking. The purpose of this study was to investigate the potential causal relationship between 45 genetically predicted dietary intake habits and thyroid diseases. We obtained GWAS data for 45 dietary intake habits from the UK Biobank and for 10 thyroid diseases from the FinnGen R12 database. We performed univariable Mendelian randomization (UVMR) using the inverse variance weighted (IVW) test as the primary test and corrected the results by false discovery rate (FDR) analysis. Additionall

SUBMITTER: Wang N 

PROVIDER: S-EPMC12907581 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature