The impact of accelerometer-derived 'weekend warrior' physical activity on musculoskeletal disorders and multimorbidity development.

ABSTRACT:

Background

Whether concentrating moderate-to-vigorous physical activity (MVPA) into 1-2 days ("weekend warrior", WW) provides musculoskeletal benefits comparable to more evenly distributed weekly activity ("regular activity", RA) remains unclear.

Methods

In a prospective UK Biobank accelerometer cohort (n = 52,606), participants free of musculoskeletal disease at baseline were classified hierarchically: inactive (<150 min/week MVPA); among those meeting the guideline threshold (≥150 min/week), WW (≥50% of weekly MVPA accrued within the most active 1-2 days) and RA (≥150 min/week but not meeting the WW criterion). Over a median 8.2 years of follow-up, there were 4107 osteoarthritis (OA), 2454 spine degenerative changes (SDCs), and 1006 osteoporosis (OP) events. Cox models est

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC12907651 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature