Clinical, Immunological and Microbiological Improvements With Zinc-Coated Healing Abutments During the Healing Phase.

ABSTRACT:

Purpose

The aim of this study was to evaluate the clinical, immunological, and microbiological effects of zinc-coated healing abutments (Zn-TiO₂ abutments) on peri-implant soft tissue as compared with the commercially used ones (Ti abutments).

Methods

The study was a prospective, non-randomised, single-centre, open-label, proof-of-concept clinical trial. The Ti and Zn-TiO₂ abutments were non-randomly connected to 2 neighbouring implants in the posterior region in each eligible patient. The bleeding-on-probing proportion (BOP%), probing pocket depth (PPD), the concentration of the pro-inflammatory cytokine (TNF-α, IL-6) in the peri-implant crevicular fluid (PICF), and the early microbial communities assessed by 16S rRNA sequencing were recorded.

Resul

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC12907655 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature