Comparison of different airway pressures in (synchronized) ventilation during cardiopulmonary resuscitation in pigs.

ABSTRACT:

Background

The optimal ventilation strategy during cardiopulmonary resuscitation (CPR) remains undetermined. Synchronizing ventilation to chest compressions has been proposed to enhance end-organ perfusion and oxygenation. This study evaluates the pulmonary function and injury in a synchronized ventilation (SV) strategy using lower peak pressure compared to chest compression synchronized ventilation (CCSV) with higher peak pressures and intermittent positive pressure ventilation (IPPV).

Materials/methods

35 pigs underwent cardiac arrest, followed by basic and advanced life support with mechanical chest compressions and ventilation according to randomized groups: IPPV (peak pressure (P _peak) 40 mbar), SV (P _peak 20 mbar), and CCSV (P

SUBMITTER: Renz M 

PROVIDER: S-EPMC12907900 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature