Structural, electronic and bioactive profiling of a 2'-hydroxychalcone-Ag composite: a DFT-supported biomedical study on anticancer, antioxidant and antibacterial activities.

ABSTRACT: Biocompatible and biologically active nanomaterials are currently in demand. This work presents the synthesis of the medicinally significant fluorophore 2'-hydroxychalcone and its subsequent composite with silver nanoparticles (chal-AgNPs) and their characterization using experimental and theoretical techniques and applications. The active organic functional groups present in the chalcone functioned as reducing and stabilizing agents in the composite with AgNPs by solution chemistry method. FESEM reveals spherically shaped and uniformly scattered nanoparticles with an average diameter of 70 nm. X-ray diffraction (XRD) patterns of chalcone-mediated AgNPs confirmed the existence of spherical AgNPs with a crystallite size of 46 nm in a face-centered cubic crystal structure. The surface plasmo

SUBMITTER: Butt AL 

PROVIDER: S-EPMC12908004 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature