The effect of gender-affirming hormonal treatment on personality traits <i>-</i> a NEO-PI-R study.

ABSTRACT:

Introduction

Gender-affirming hormone therapy is a crucial component of the medical transition for many transgender individuals. While there are well-established differences in personality traits between cisgender men and women, the effects of gender-affirming hormone therapy on these traits in transgender individuals remain largely unexplored.

Aims

The primary aim of this study was to investigate whether gender-affirming hormone therapy affects personality traits in transgender individuals.

Materials and methods

Adult transgender persons referred for gender-affirming hormone therapy to ANOVA, Center for Andrology, Sexual Medicine, and Trans Medicine at Karolinska University Hospital, Stockholm, Sweden, completed the NEO-PI-R inventory once before starting hormone the

SUBMITTER: Holmberg M 

PROVIDER: S-EPMC12908070 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature