Left ventricular and atrial strain and the risk of mortality and rehospitalization in heart failure.

ABSTRACT:

Background

Global longitudinal strain (GLS) and left atrial strain metrics, including reservoir (LAr), contraction (LAct), and conduit strain (LAcd), have emerged as key indicators of left ventricular (LV) function and filling pressures. However, the prognostic value of these markers for risk stratification in acute heart failure (HF) remains uncertain, particularly in identifying patients at elevated risk of rehospitalization and mortality.

Results

In the prospective HARVEST cohort study, LA strain and GLS measurements were obtained retrospectively in 141 patients (mean age 71 ± 13, 25% women). Strain values are reported as absolute values reflecting the magnitude of deformation regardless of sign. Multivariable adjusted Cox regression was used to test whether GLS, LAr, LAc

SUBMITTER: Zilic H 

PROVIDER: S-EPMC12908388 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature