Ontology highlight
ABSTRACT: Background
The multistage model of substance use proposes that reinforcement mechanisms and motives for use change as individuals develop substance use disorders, with positive reinforcement driving substance use when substance use disorder symptoms are absent/mild and negative reinforcement becoming dominant when substance use disorder symptoms are more severe. We aimed to determine whether event-level associations between affect, cannabis use, motives for use, and heaviness of use were moderated by cannabis use problem severity, consistent with the multistage model of substance use.Methods
We used EMA data (2 observations per day for 14 days) from 571 young adult females who regularly used cannabis. The sample included a majority sexual minority women and gender diverse i
SUBMITTER: Dyar C
PROVIDER: S-EPMC12908467 | biostudies-literature | 2026 Jan
REPOSITORIES: biostudies-literature