Health-related quality of life and cognitive functioning in survivors of oligodendroglioma: An international cross-sectional investigation.

ABSTRACT:

Background

Patients with oligodendroglioma have a relatively favorable prognosis. The long-term impacts of the tumor itself and its treatment on health-related quality of life (HRQOL) and cognition remain largely unclear. We investigated associations between treatment and functioning of survivors of oligodendroglioma.

Methods

In this cross-sectional observational study, patients with oligodendroglioma, isocitrate dehydrogenase-mutant and 1p/19q-codeleted, diagnosed ≥ 5 years ago, were recruited. Patients completed patient-reported outcome measures (EORTC QLQ-C30; BN20; MOS Cognitive Complaints Scale) and cognitive tests (HVLT-R, TMT, COWAT). Associations between HRQOL and cognition outcomes, and clinical variables (time since diagnosis; age at diagnosis; progression; tumor l

SUBMITTER: Boele FW 

PROVIDER: S-EPMC12908480 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature