Longitudinal Cognitive Recovery After Critical Illness: Trajectories in Sepsis and Non-Sepsis Survivors.

ABSTRACT: BackgroundPost-critical illness cognitive dysfunction (PCICD) is a frequent and debilitating outcome among survivors of critical illness. Although sepsis has been associated with poor cognitive outcomes, its independent contribution remains unclear due to overlapping clinical factors. This study sought to characterize cognitive recovery trajectories over 12 months after intensive care.MethodsIn this single-center prospective cohort study, adult ICU survivors were assessed at 1, 3, 6 and 12 months post-discharge using telephone-administered Mini-Mental State Examination (MMSE) or Montreal Cognitive Assessment (MoCA-Blind). Total scores were standardized within instrument (z-scores). Linear mixed-effects models evaluated change in z-scores over time. Domain-specific analyses ex

SUBMITTER: Sahu R 

PROVIDER: S-EPMC12908703 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature