An 18F-FDG PET/CT-based radiomics nomogram for predicting progression-free survival in nasopharyngeal carcinoma: A retrospective cohort study.

ABSTRACT: This study aimed to develop and validate a positron emission tomography/computed tomography (PET/CT)-based nomogram for individualized prediction of 3-year progression-free survival (PFS) in patients with nasopharyngeal carcinoma (NPC). A total of 128 patients with NPC who underwent pretreatment PET/CT imaging were retrospectively enrolled. Radiomic features were extracted from PET and CT images, and clinical variables were collected. Feature selection was performed using univariate Cox analysis, multivariable Cox analysis, and the least absolute shrinkage and selection operator regression to identify independent predictors. A nomogram was constructed by integrating CT-Radscore, PET-Radscore, and key clinical variables. Model performance in predicting 3-year PFS was evaluated using the con

SUBMITTER: Lin J 

PROVIDER: S-EPMC12908803 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature