Membrane-permeable trehalose 6-phosphate precursor spray increases wheat yields in field trials.

ABSTRACT: Trehalose 6-phosphate (T6P) is an endogenous sugar signal in plants that promotes growth, yet it cannot be introduced directly into crops or fully genetically controlled. Here we show that wheat yields were improved using a timed microdose of a plant-permeable, sunlight-activated T6P signaling precursor, DMNB-T6P, under a variety of agricultural conditions. Under both well-watered and water-stressed conditions over 4 years, DMNB-T6P stimulated yield of three elite varieties. Yield increases were an order of magnitude larger than average annual genetic gains of breeding programs and occurred without additional water or fertilizer. Mechanistic analyses reveal that these benefits arise from increased CO₂ fixation and linear electron flow ('source') as well as from increased starchy

SUBMITTER: Griffiths CA 

PROVIDER: S-EPMC12909131 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature