NOD-like receptor repertoire in the chromosome-level genome of the demosponge <i>Dysidea avara</i> (Schmidt, 1862).

ABSTRACT: Porifera, one of the earliest diverging metazoans, have shown a surprisingly complex immune repertoire. However, most information to date is based on de novo transcriptome assemblies, limiting our knowledge regarding the presence and evolution of poriferan immune repertoire. Here, we generated the chromosome-level genome of the demosponge Dysidea avara, a target species in studies on symbiosis and differential expression of immune genes. We examined the presence and the number of common immune protein domains in the annotated genome of D. avara, and we further focused on NOD-like Receptors (NLRs), which are one of the most expanded immune receptors in Porifera according to previous reports on draft genomes and transcriptome assemblies. Dysidea avara has a 575 Mb

SUBMITTER: Koutsouveli V 

PROVIDER: S-EPMC12909245 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature