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An interactive cascaded deep learning framework with expert refinement for accurate striatal subregion segmentation.


ABSTRACT:

SUBMITTER: Kim J 

PROVIDER: S-EPMC12909890 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature

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An interactive cascaded deep learning framework with expert refinement for accurate striatal subregion segmentation.

Kim Jungeun J   Kim Daewoon D   Kim Sungyu S   Suh Minseok M   Yoo Sang-Won SW   Lee Jae Sung JS   Yoon Hyung-Jin HJ  

Scientific reports 20260128 1


Accurate delineation of striatal subregions in brain MRI is essential for reliable dopaminergic PET quantification and the assessment of neurodegenerative disorders such as Parkinson’s disease. In this study, we introduce StriaSeg-iARM, a cascaded deep learning framework designed for high-precision segmentation of 12 anatomically defined striatal subregions in native space. The model employs a two-stage 3D residual U-Net architecture, where the first stage localizes the striatum and the second p  ...[more]

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