Structured Exercise During Chemotherapy for Locally Advanced or Metastatic Pancreatic Cancer: A Single-Arm, Feasibility Trial.

ABSTRACT:

Introduction

Evidence on structured exercise during systemic treatment for patients with locally advanced or metastatic pancreatic cancer is still limited, and detailed feasibility data in real-world clinical settings remain scarce. This study aimed to assess the feasibility, safety, and preliminary efficacy of a 12-week exercise intervention in this population.

Methods

In this prospective single-arm trial, 20 patients undergoing chemotherapy participated in a supervised exercise program comprising aerobic and resistance training, delivered twice weekly for 12 weeks. Participants could choose between supervised gym-based or home-based sessions. Primary outcomes included recruitment, retention, attendance, adherence, tolerance, and safety. Secondary outcomes were changes in p

SUBMITTER: Borsati A 

PROVIDER: S-EPMC12910164 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature