Noninvasive BCI-based cognitive rehabilitation in poststroke cognitive impairment: study protocol for a randomized controlled trial.

ABSTRACT:

Background

Poststroke cognitive impairment (PSCI) significantly reduces quality of life and survival rates. Current interventions face challenges in efficacy and accessibility. Noninvasive brain-computer interface (BCI) technology may enhance neural plasticity and cognitive recovery through real-time neurofeedback, offering a safe and accessible approach for poststroke cognitive rehabilitation. This trial aims to evaluate the efficacy of BCI-based cognitive training and explore its neural mechanisms.

Methods

A prospective, randomized, double-blind, controlled, single-center trial will enroll 66 PSCI patients. Participants will be randomized into the intervention group or control group. Interventions will be administered 5 days/week for 4 weeks. Primary outcome is as follows:

SUBMITTER: Niu X 

PROVIDER: S-EPMC12911009 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature