Harnessing Bacterial Lipid Coatings on Gold Nanoparticles for Enhanced Cell Adhesion Applications.

ABSTRACT: Antimicrobial resistance (AMR) is a global health challenge responsible for millions of deaths annually. Hence, there is an urgent need for improved strategies to combat AMR. Nanoparticle (NP)-based drug delivery has shown promise for enhancing the efficacy of conventional antibiotic treatments. Moreover, lipid functionalization of NP surfaces can enhance drug loading, colloidal stability, and specificity. Cell membrane vesicles as the outer shell coating for NPs provokes a unique interaction between fabricated NPs and their respective parent bacteria. Despite numerous studies having investigated the use of bacterial extracellular vesicle coatings for drug delivery, to the best of our knowledge, the potential of isolated bacterial membrane lipids has not yet been explored. This study inves

SUBMITTER: Gharehgozlo S 

PROVIDER: S-EPMC12911120 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature