Bio-Assisted Synthesis of Reduced Graphene Oxide Nanosheets From Graphene Oxide: Promising and Efficient Cytotoxic and Antidiabetic Potency in In Vitro, Kinetic, and In Silico Models.

ABSTRACT: Green chemistry has recently made strides in the sustainable synthesis of next-generation nanomaterials using reducing agents sourced from plants. Biocompatible conversion of reduced graphene oxide from graphene oxide nanomaterials is of particular interest in medical applications. The leaf extract of C. igneus functions as a reducing agent to produce reduced graphene oxide nanosheets from its precursor graphene oxide. A variety of characterization techniques were employed to confirm the formation and stability of reduced graphene oxide nanosheets. The cytotoxicity and glucose uptake potential of nanosheets have been evaluated through in vitro cell-based assays. The MTT assay revealed a concentration-dependent cytotoxic effect on Chang liver and U87MG cells, with maximum 84.5% and 7

SUBMITTER: Yadav M 

PROVIDER: S-EPMC12911526 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature