Safety and Glycemic Outcomes of the MiniMed 780G System with a Disposable All-in-One Sensor.

ABSTRACT:

Introduction

The present study assessed the impact of the disposable Simplera Sync™ sensor with the MiniMed™ 780G (MM780G) advanced hybrid closed-loop (AHCL) system on type 1 diabetes (T1D) glycemic metrics, insulin delivery, and safety.

Materials and methods

Youths (aged 7-17 years) and adults (aged 18-80 years) with T1D were enrolled in this single-arm, nonrandomized study at 24 sites in the United States. Participants began with an ∼2-week run-in period where hybrid closed-loop (HCL; auto basal only) or open-loop insulin delivery was used, followed by an ∼3-month study period with AHCL activated. Glycemic outcomes and insulin delivery during the last 6-7 weeks of the study, when settings were optimized at investigator's discretion, were compared with the run-in. Glycemic

SUBMITTER: Nally LM 

PROVIDER: S-EPMC12911630 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature