Improvements in quality-of-life dimensions through medium-chain triglyceride (MCT) supplementation in rheumatoid arthritis: updated findings from a randomised clinical trial.

ABSTRACT:

Objective

To assess the impact of medium-chain triglycerides (MCTs) and fibre on health-related quality of life (QOL), morning stiffness and pain in rheumatoid arthritis (RA) patients.

Methods

A randomised, double-blind, placebo-controlled clinical trial enrolled 61 RA patients on stable drug treatment. Participants received twice-daily MCT supplementation (30 g/day) for 8 weeks, followed by 8 weeks of MCTs (30 g/day) combined with fibre (30 g/day). The control group received the same supplementation as the test group, with long-chain triglycerides instead of MCTs. QOL parameters, morning stiffness, pain intensity and lipid profile were assessed at baseline (T0), week 8 (T2) and week 16 (T4).

Results

After 16 weeks, the test group showed statistically and clinically s

SUBMITTER: Gaudioso G 

PROVIDER: S-EPMC12911760 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature