Direct metathesis of carbon-carbon <i>σ</i>-bonds at a versatile macrocycle-supported diiron platform.

ABSTRACT: The metathesis of C-C σ-bonds holds potential as an atom-economical strategy for molecular engineering. While this reaction has been achieved in industrial and research settings, the former is energy-intensive and the latter has only been reported to operate either indirectly, proceeding through well-known π-bond metathesis chemistry, or through the use of structural/electronic factors that assist in C-C bond activation (e.g. anchimeric effects, directing groups, photochemical effects, etc.). Herein, we report the first example of a direct, thermodynamically favored C-C σ-bond metathesis reaction in which the C(sp)-C(sp²) bonds of diarylacetylenes are selectively cleaved before their fragments are metathesized and C(sp)-C(sp²) linkag

SUBMITTER: Liu T 

PROVIDER: S-EPMC12911874 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature