Impact of oxidative stress on <i>Magnetospirillum gryphiswaldense</i> MSR-1 physiology and magnetosome biomineralization at the single-cell level.

ABSTRACT: Magnetotactic bacteria, such as Magnetospirillum gryphiswaldense MSR-1, naturally produce magnetosomes-intracellular magnetic nanoparticles that enable navigation within geomagnetic fields. Magnetosomes hold significant potential for biomedical and biotechnological applications; however, key aspects of their biomineralization remain poorly understood. This study investigates how oxidative stress, induced by hydrogen peroxide and iron, influences magnetosome formation and bacterial physiology under aerobic and microaerobic conditions. Single-cell advanced microscopy and high-throughput techniques revealed that microaerobic conditions supported robust magnetosome production and larger magnetite crystals while maintaining low oxidative stress levels. In contrast, aerobic conditions sup

SUBMITTER: Maso-Martinez M 

PROVIDER: S-EPMC12912731 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature