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ABSTRACT: Background
The relationship between media portrayal of psychedelic drugs, scientific research and drug policy is an area of debate.Aims
To apply artificial intelligence technology to measure trends in media sentiment towards the therapeutic potential of psychedelic drugs.Method
Up to 300 of the most relevant articles from Google News searches for the term 'psychedelics' were sampled for each year from 2000 to 2025. A large language model, ChatGPT, evaluated subject matter and sentiment.Results
In total, 88.3% of screened URLs (3308 of 3747) were included in the analysis. The proportion of articles focusing on the therapeutic potential of psychedelics increased from 13.3% (26 of 198) from 2000 to 2009 to 85.3% (1254 of 1470) from 2020 to 2025. The average sentiment score from 2000 to 2025 for articles from all publications (N = 2168) was 78.5 ± 9.3 (mean ± s.d.) (possible range: 1-100). 1.3% (29 of 2168) of articles carried negative sentiment (<50) whereas 4.8% (103 of 2168) had extremely positive sentiment (≥90). Average sentiment reached a peak in 2020 (80.8 ± 7.0), and a statistically significant trough in sentiment was observed in 2024 relative to 2020-2023 (2020-2023, 79.2; 2024, 74.3, P < 0.00001, Mann-Whitney U-test). The proportion of negative-neutral articles (≤65) increased annually from a trough of 3.6% (8 of 267) in 2020 to a peak of 20.9% (43 of 253) in 2024. Artificial intelligence sentiment scores were correlated and concordant with average human rater scores (r = 0.88, concordance correlation coefficient 0.84).Conclusions
Although most 21st-century media coverage of psychedelic drugs has been positively framed, negative and neutral coverage has increased in frequency since 2020. Researchers, clinicians, regulators and policy-makers should be mindful of the complex relationship between media portrayals of psychedelics and the results of scientific research.
SUBMITTER: Bender DA
PROVIDER: S-EPMC12912910 | biostudies-literature | 2026 Feb
REPOSITORIES: biostudies-literature

BJPsych open 20260212 2
<h4>Background</h4>The relationship between media portrayal of psychedelic drugs, scientific research and drug policy is an area of debate.<h4>Aims</h4>To apply artificial intelligence technology to measure trends in media sentiment towards the therapeutic potential of psychedelic drugs.<h4>Method</h4>Up to 300 of the most relevant articles from Google News searches for the term 'psychedelics' were sampled for each year from 2000 to 2025. A large language model, ChatGPT, evaluated subject matter ...[more]