Sex-dependent associations of childhood maltreatment with obesity-related traits: results from the German National Cohort (NAKO).

ABSTRACT:

Background

The relationship between childhood maltreatment (CM) and obesity is nuanced, and recent evidence suggests stronger associations between CM and obesity-related traits in females compared to males. This study aims to validate and extend these findings in a large sample from the German National Cohort (NAKO).

Methods

The NAKO is a population-based cohort study including 204,744 adults. For the present analyses, 151,143 individuals (74,596 female) were included. CM was assessed using the Childhood Trauma Screener (CTS). From the CTS, an overall severity score (CTS sum score), a cumulative CM score (number of CM subtypes with at least moderate severity), and five CTS subtypes were considered as exposures. Obesity-related traits included anthropometric (height, weight,

SUBMITTER: Topfer P 

PROVIDER: S-EPMC12913021 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature