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Early major adverse kidney events after lung transplantation: risk of chronic kidney disease and prognostic impact.


ABSTRACT:

Objective

Renal dysfunction, including acute kidney injury (AKI) and chronic kidney disease (CKD), is a major complication following lung transplantation (LT) and is associated with increased morbidity and mortality. This study aims to evaluate the clinical significance of AKI in relation to the development of post-LT CKD and poor prognosis.

Methods

Among 133 patients who underwent LT, 116 were included in the analysis. AKI was defined according to the Kidney Disease Improving Global Outcomes criteria. AKI was classified into early AKI (E-AKI), occurring within a few hours to one week postoperatively, and late AKI (L-AKI), occurring between one week and one month after LT. The Major Adverse Kidney Event within 30 days following LT (MAKE30)-a composite outcome that includes a

SUBMITTER: Shimada Y 

PROVIDER: S-EPMC12913340 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature