Primary angiitis of the central nervous system: predictors of stroke during immunosuppressant treatment.

ABSTRACT:

Objective

To evaluate predictors of ischemic stroke in patients with primary angiitis of the central nervous system after initiation of immunosuppressive therapy.

Materials and methods

This retrospective study included 204 MRI examinations of 23 patients with primary angiitis of the central nervous system, treated with immunosuppressive therapy between 2015 and 2020 at the University Hospital Bern and the Cantonal Hospital St. Gallen, Switzerland. Two senior neuroradiologists evaluated the MRI exams with regard to the occurrence and location of ischemic stroke and hemorrhage, as well as the following characteristics of inflamed vessels on 3D time-of-flight angiography and T1 dark-blood post contrast: signal intensity of vessel walls, length of enhancement, circular extent of

SUBMITTER: Wagner F 

PROVIDER: S-EPMC12913815 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature