Comparison of novel nutritional index (TCBI) and insulin resistance index (TyG-BMI) for assessing cardiovascular disease risk: a cohort study.

ABSTRACT:

Background

Cardiovascular disease (CVD) is a leading cause of death and disability worldwide, particularly among middle-aged and elderly populations. And early risk assessment is essential for early intervention and effective prevention. This study aims to investigate and compare the associations of the triglyceride, total cholesterol and body weight index (TCBI), a novel nutritional index, and the widely researched insulin resistance index-triglyceride glucose-body mass index (TyG-BMI) with CVD risk.

Methods

Using data from the CHARLS (2011-2020), including 8,104 participants without CVD at baseline. The associations of TCBI and TyG-BMI with CVD risk were assessed using Cox proportional hazards models and restricted cubic spline (RCS) analysis. Additionally, receiver operat

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12914969 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature