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Effectiveness of differentiated antiretroviral therapy delivery models for stable persons living with HIV in Africa: a systematic review and meta-analysis.


ABSTRACT:

Introduction

Fundamental progress has been made in HIV care, and one of the major advances was the implementation of Differentiated Service Delivery (DSD) models. DSD models are important in reducing cost in resource-limited countries. However, evidence on the effectiveness of DSD models on stable Persons Living with HIV (PLWH) in comparison with conventional HIV care is limited. Thus, a systematic review and meta-analysis of randomized controlled trials was conducted to assess whether DSD models are more effective than conventional care in improving viral suppression, retention in care, and adherence among stable PLWH in Africa.

Methods

A comprehensive search was conducted using PubMed, Embase, Scopus, Cochrane, Research4Life, and Google Scholar. In this study, randomized c

SUBMITTER: Nega AD 

PROVIDER: S-EPMC12915025 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature