A One Health comparative genomic assessment of antimicrobial-resistant <i>Escherichia coli</i> in dairy farms in western Canada.

ABSTRACT: Antimicrobial resistance (AMR) is a growing global public health concern affecting animals, humans, and the environment. Given its ubiquity, Escherichia coli may play a key role in the dissemination of AMR across these domains. Peri-urban regions where urban and rural systems intersect present unique challenges for controlling AMR. Despite this, limited data are available on AMR dissemination across the One Health continuum in peri-urban settings such as the Fraser Valley region of Canada. This study adopted a One Health approach to assess associations in AMR traits between E. coli from dairy production systems, nearby natural environments, and peri-urban communities within the same geographic location and timeframe. Over 1,000 isolates were recovered, and 421 were whole-geno

SUBMITTER: Klaas C 

PROVIDER: S-EPMC12915320 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature