Novel 3D magnetic resonance fingerprinting radiomics in adult brain tumors: a feasibility study.

ABSTRACT:

Objectives

To test the feasibility of using 3D MRF maps with radiomics analysis and machine learning in the characterization of adult brain intra-axial neoplasms.

Methods

3D MRF acquisition was performed on 78 patients with newly diagnosed brain tumors including 33 glioblastomas (grade IV), 6 grade III gliomas, 12 grade II gliomas, and 27 patients with brain metastases. Regions of enhancing tumor, non-enhancing tumor, and peritumoral edema were segmented and radiomics analysis with gray-level co-occurrence matrices and gray-level run-length matrices was performed. Statistical analysis was performed to identify features capable of differentiating tumors based on type, grade, and isocitrate dehydrogenase (IDH1) status. Receiver operating curve analysis was performed and the ar

SUBMITTER: Tippareddy C 

PROVIDER: S-EPMC12915495 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature