The burden of sleep disturbances on quality of life and mental well-being in nearly 50,000 perimenopausal and postmenopausal women with and without concurrent vasomotor symptoms from the United States and Europe.

ABSTRACT:

Objectives

To quantify the burden of sleep disturbances on health-related quality of life (HRQoL) and mental well-being in perimenopausal and postmenopausal women with/without co-occurring vasomotor symptoms (VMS).

Methods

Perimenopausal and postmenopausal women aged 40 to 65 years who participated in the National Health and Wellness 2019/2021 (US; N=27,621) and 2017/2020 cross-sectional surveys (France, Germany, Italy, Spain, UK; N=20,220) were included. Patient-reported outcomes were HRQoL (Short-Form Health Survey physical and mental component summary scores, EuroQol Visual Analogue Scale, EQ-5D-5L), depression (Patient Health Questionnaire-9), and anxiety (Generalized Anxiety Disorder-7 assessment). Associations between self-reported sleep disturbances and/or VMS and stu

SUBMITTER: Soares CN 

PROVIDER: S-EPMC12915534 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature