Compound probiotics alleviate <i>Escherichia coli</i>-induced diarrhea in calves by modulating tryptophan and bile acid metabolism of the fecal microbiota.

ABSTRACT: Calf diarrhea, particularly that caused by diarrheagenic Escherichia coli, has become a major issue affecting the sustainable development of the calf farming industry. Although the use of traditional antimicrobial agents can alleviate symptoms, challenges such as antibiotic resistance, drug residues, and intestinal microbiota dysbiosis urgently need to be addressed. Therefore, this study investigates the mechanism by which compound probiotics alleviate diarrheagenic Escherichia coli-induced diarrhea in calves. Compound probiotics were administered to calves with diarrheagenic Escherichia coli-induced diarrhea, and their effects on growth performance, intestinal microbiota structure, and metabolic profiles were evaluated. The results showed that compound probiotic inter

SUBMITTER: Zhong J 

PROVIDER: S-EPMC12915837 | biostudies-literature | 2026 Dec

REPOSITORIES: biostudies-literature