2Pipe starts with a question: matching you with the correct pipeline for MAG reconstruction.

ABSTRACT: Whole-genome sequencing has boosted our ability to explore microbial diversity by enabling the recovery of metagenome-assembled genomes (MAGs) directly from environmental DNA. As a result, the vast availability of sequencing data has prompted the development of numerous bioinformatics pipelines for MAG reconstruction, along with challenges to identify the most suitable pipeline to perform the analysis according to the user needs. This report briefly discusses the computational requirements of these pipelines; presents the variety of interfaces, workflow managers, and package managers they feature; and describes the typical modular structure. Also, it provides a compacted technical overview of 41 publicly available pipelines or platforms to build MAGs starting from short and/or long sequenc

SUBMITTER: Yepes-Garcia J 

PROVIDER: S-EPMC12915991 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature