Diagnostic accuracy of nucleic acid amplification tests for human intestinal nematode infections: A systematic review and meta-analysis.

ABSTRACT:

Introduction

The use of diverse diagnostic methods in the absence of a definitive gold standard makes it challenging to determine the most appropriate test for diagnosing human intestinal nematode infections (HINIs), particularly across various clinical settings with varying endemicity. The ideal diagnostic method should be feasible, cost-effective, and accurate. This review evaluates the diagnostic accuracy of nucleic acid amplification tests (NAATs), comparing them to the Kato-Katz (KK) and flotation methods for the detection of ascariasis, trichuriasis, and hookworm infection, the Baermann technique (BT) for strongyloidiasis, the Scotch tape test for enterobiasis, and a composite reference standard (CRS).

Methods

We systematically searched PubMed, CINAHL, Scopus, Trip, We

SUBMITTER: Jayakody N 

PROVIDER: S-EPMC12916058 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature