Psychomotor Speed From Minimal Hepatic Encephalopathy Testing Is Associated With Physical Frailty in Patients With Advanced Chronic Liver Disease.

ABSTRACT:

Introduction

Physical frailty and minimal hepatic encephalopathy (MHE) are common in advanced chronic liver disease (AdvCLD). Although the Psychometric Hepatic Encephalopathy Score is used for MHE diagnosis, its complexity limits routine use. The Stroop EncephalApp (StE) offers a simpler method for MHE diagnosis. We aimed to investigate the association between MHE using the StE and physical frailty by the Liver Frailty Index (LFI), in patients with AdvCLD.

Methods

This multicenter study analyzed data from patients with AdvCLD awaiting liver transplantation. Patients were categorized into 2 groups based on the presence or absence of MHE and compared using the LFI and its components. To identify factors influencing the various StE modalities and MHE diagnosis, we used the Spea

SUBMITTER: Sogbe M 

PROVIDER: S-EPMC12916095 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature