Health-related quality of life scores of ultralow rectal cancer patients after conformal sphincter preservation operation compared to newly derived preoperative EORTC QLQ-C30, CR38 reference values and EORTC QLQ-C30 norm.

ABSTRACT:

Background

Postoperative quality of life (Post-QoL) is the key to measuring the effectiveness of sphincter-preserving operation such as Conformal sphincter preservation operation (CSPO) for ultralow rectal cancer. This study aimed to establish preoperative QoL (Pre-QoL) reference values for rectal cancer patients and compare them with post-CSPO QoL to highlight CSPO's benefits in preserving QoL.

Methods

Clinical baseline data and Post-QoL data (EORTC QLQ-C30, CR38) from ultralow rectal cancer patients who underwent CSPO at Shanghai Changhai Hospital from August 2011 to April 2020 were retrospectively collected, and Pre-QoL reference values for rectal cancer patients were extracted through a literature review. The Post-QoL of CSPO were compared with the newly derived Pre-QoL

SUBMITTER: Ding HB 

PROVIDER: S-EPMC12916371 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature