Lateral ventricular choroid plexus enlargement in patients with spontaneous intracranial hypotension.

ABSTRACT:

Objective

This study aimed to evaluate the choroid plexus volume in patients with spontaneous intracranial hypotension (SIH), including the lateral, third, and fourth ventricles, and explore its potential relationship with clinical characteristics.

Background

SIH is caused by cerebrospinal fluid (CSF) leaks. The choroid plexus is predominantly responsible for CSF production and has been implicated in altered CSF dynamics in various neurological conditions.

Methods

This retrospective case control study included 25 patients with SIH who were diagnosed between 2022 and 2024 from a single tertiary center. In addition, 25 age- and sex-matched healthy controls were included. Choroid plexus volumes were manually segmented from 3D contrast-enhanced magnetization-prepared rapi

SUBMITTER: Yoon S 

PROVIDER: S-EPMC12916456 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature