Cognitive arbitration between candidate dimensions of psychopathology.

ABSTRACT: As an alternative to the Diagnostic and Statistical Manual of Mental Disorders, transdiagnostic approaches that identify latent dimensions of psychopathology through factor analysis have gained prominence in recent years. A key critique of these approaches, however, is that they are performed at the level of symptoms only. This begs the question: are these dimensions truly more valid predictors of external outcomes than existing alternatives? Are there other ways, that are more data-driven, which can allow us to refine our definitions of clinical phenotypes? We tested this idea empirically, conducting a large-scale meta-scientific comparison of thousands of competing factor solutions that allowed us to determine if the latent structure underlying the covariation of psychiatric symptoms has

SUBMITTER: Fox CA 

PROVIDER: S-EPMC12916499 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature